Jill M. Brown

The paper uses live-cell imaging to study transcriptional bursting dynamics during mouse erythropoiesis, finding changes in burst patterns associated with differentiation stages.

The paper identifies linked chromatin domains (CDs) with nanoscale functional topography in somatic cells, showing cohesin and histone modifications are confined to surfaces and enriched in cores, independent of cohesin.

This paper applies object detection networks to classify and localize cells in fluorescence microscopy, demonstrating effectiveness with small datasets and integrating an AR system for real-time imaging.

This study investigates ATR-16 syndrome, finding that deletion size correlates with severity but no critical region defines the phenotype, and genetic background significantly affects outcomes.

This study models erythropoiesis in CDA-I by analyzing patient-derived erythroblasts, identifying abnormalities in DNA accessibility, proliferation, and enucleation, with genotype-phenotype correlations.

The paper develops Tri-C, a single-cell 3C method, to reveal dynamic chromatin interactions and regulatory hubs in mammalian cells.