ImmunologyPLoS ONEPeer-reviewed
Human resistin is critical to activation of the NLRP3 inflammasome in macrophages
Udeshika Kariyawasam, JOHN T. SKINNER, Winson Lam…·Roger A. Johns
This study identifies hResistin's role in priming and activating the NLRP3 inflammasome in macrophages, linking it to inflammatory diseases through HMGB1, BTK, and downstream cytokine production.