Author

Roger A. Johns

Johns Hopkins UniversityORCID 0000-0001-9232-2434Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:rat· 1

Frequent Co-Authors

Adam AndruskaiD· 1 shared Aiqing Cao· 1 shared Andrea L. CoxiD· 1 shared Cerianne Huang· 1 shared Dan YiiD· 1 shared Dongeon KimiD· 1 shared Evan Bao· 1 shared Hanqiu Zhao· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperDevelopmental Biology

Adam AndruskaORCID

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2 papers

Recent·Most cited

Human resistin is critical to activation of the NLRP3 inflammasome in macrophages

Udeshika Kariyawasam, JOHN T. SKINNER, Winson Lam, Rituparna Chakrabarti, Andrea L. Cox, Paul M. Hassoun, Qing Lin, Roger A. Johns

This study identifies hResistin's role in priming and activating the NLRP3 inflammasome in macrophages, linking it to inflammatory diseases through HMGB1, BTK, and downstream cytokine production.

PLoS ONE · Apr 10, 2026Peer-reviewedImmunology

EBF1 controls an embryonic artery-forming niche that reactivates in pulmonary arterial hypertension

Wen Tian, Ting-Hsuan Wu, Shenbiao Gu, Seunghee Lee, Hanqiu Zhao, Adam Andruska, Kyle K. Song, Jason Chang, Cerianne Huang, Ryan Vinh, Dongeon Kim, Yu Zhu, Evan Bao, Stuti Agarwal, Dan Yi, , Mark Robert Nicolls

This study identifies EBF1 as a regulator of embryonic artery formation and shows its reactivation in pulmonary arterial hypertension drives pathological vascular remodeling.

bioRxiv · May 2, 2025 · PreprintDevelopmental Biology