Sven Dennerlein

The paper maps the human mitochondrial complexome at super-resolution, revealing protein complexes, networks, and interactions involved in mitochondrial function and disease.

This study elucidates the mechanism of human tRNA 3'CCA maturation by determining TRNT1 structures and showing a continuous polymerization and translocation mechanism.

This study uses super-resolution microscopy to visualize mitochondrial mRNAs and their interactions with proteins, revealing dynamic changes in mRNA distribution and structure during apoptosis and in disease.