Deep Learning Enabled 3D Multi-Omic Analysis Reveals Molecular Signatures of Heterogeneous Response to Chemotherapy in Pancreatic Cancer
André Forjaz, Hengameh Mojdeganlou, Alens Valentin, Meredith Wetzel, Dmitrijs Lvovs, Atul M. Deshpande, Sarah M. Shin, Sujan Piya, Kimal Rajapakshe, Paola Guerrero, Brian A. Pedro, Dimitrios N. Sidiropoulos, Pei-Hsun Wu, Vincent Bernard Pagan, Demystifying Pancreatic Cancer Therapies TeamLab, , Laura DeLong Wood
The paper develops a 3D multi-omic pipeline using deep learning to analyze chemotherapy response in pancreatic cancer, identifying molecular signatures of resistance and fibroblast-cancer interactions.
bioRxiv · Mar 5, 2026 · PreprintCancer Biology