Author

Shreyasee V. Kumbhar

The University of Texas MD Anderson Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Hikaru SugimotoiD· 3 shared Kent A. Arian· 3 shared Krishnan K. MahadevaniD· 3 shared Raghu KalluriiD· 3 shared Sami J. MorseiD· 3 shared Aaron A. Bickert· 2 shared Amari M. SockwelliD· 2 shared Anirban MaitraiD· 2 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Hikaru SugimotoORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintFeb 28, 2025

Distinct small molecule inhibitors of Kras specifically prime CTLA4 blockade therapy to transcriptionally reprogram Tregs and overcome resistance to suppress pancreas cancer

Krishnan K. Mahadevan, Ana S. Maldonado, Bingrui Li…·Raghu Kalluri

This study identifies small molecule Kras inhibitors that synergize with anti-CTLA4 therapy to reprogram Tregs and enhance immunotherapy efficacy in PDAC.

7 citations

humanATAC-seq

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Cancer BiologybioRxivPreprintJan 29, 2025

CDK8 remodels the tumor microenvironment to resist the therapeutic efficacy of targeted KRASG12D inhibition in pancreatic ductal adenocarcinoma

Kathleen M. McAndrews, Krishnan K. Mahadevan, Bingrui Li…·Raghu Kalluri

This study investigates how CDK8 remodels the tumor microenvironment to resist KRASG12D inhibition in PDAC, showing that targeting CDK8 can overcome resistance and improve survival.

4 citations

humanspatial transcriptomics

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ImmunologyJournal of Controlled ReleasePeer-reviewedAug 30, 2024

Development of an engineered extracellular vesicles-based vaccine platform for combined delivery of mRNA and protein to induce functional immunity

Xin Luo, Kathleen M. McAndrews, Kent A. Arian…·Raghu Kalluri

This paper develops an engineered extracellular vesicles-based vaccine platform for combined mRNA and protein delivery, showing tumor regression and immune responses in preclinical models.

30 citations

mousenon-human primate

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