A conditional, myeloid-cell specific estrogen receptor α deletion reprograms the liver immune microenvironment and impedes the growth of colon carcinoma liver metastases
Orçun Haçarız, Megan Kalaw, Qin Yang…·Pnina Brodt
This study shows that deleting estrogen receptor α in myeloid cells reduces liver metastases by altering the immune microenvironment and increasing cytotoxic T and NK cells.