Author

David G. Westbrook

University of Alabama at Birmingham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:protein structure· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Adam R. WendeiD· 1 shared Alessia FornoniiD· 1 shared Alexander GrabneriD· 1 shared Alexis J. Sloan· 1 shared Brian A. CzayaiD· 1 shared Christian FauliD· 1 shared Christopher Yanucil· 1 shared Dominik KentrupiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Adam R. WendeORCID

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2 papers

Recent·Most cited

Alpha-synuclein preformed fibril-induced aggregation and dopaminergic cell death in cathepsin D overexpression and ZKSCAN3 knockout mice

Toni Mueller, Parker Jeffrey, Yecheng He, Xiaosen Ouyang, David G. Westbrook, Victor M. Darley-Usmar, Matthew S. Goldberg, Laura A. Volpicelli‐Daley, Jianhua Zhang

This study investigates whether enhancing cathepsin D or disrupting ZKSCAN3 in the CNS can reduce α-synuclein aggregation and dopaminergic neurodegeneration, but finds no significant effect.

bioRxiv · Sep 18, 2024 · PreprintNeuroscience

FGF21-FGFR4 signaling in cardiac myocytes promotes concentric cardiac hypertrophy in mouse models of diabetes

Christopher Yanucil, Dominik Kentrup, Xueyi Li, Alexander Grabner, Karla J. Schramm, Eliana Cecilia Martinez, Jinliang Li, Isaac D. Campos, Brian A. Czaya, Kylie Heitman, David G. Westbrook, Adam R. Wende, Alexis J. Sloan, Johanna M. Roche, Alessia Fornoni, , Christian Faul

This study shows that FGF21-FGFR4 signaling in cardiac myocytes causes concentric hypertrophy in diabetic mice, suggesting it may contribute to HFpEF and that FGFR4 blockade could be a therapeutic target.

Scientific Reports · May 5, 2022Peer-reviewedMolecular Biology