Author

Gwo‐Yu Chuang

National Institutes of HealthORCID 0000-0003-0375-1013Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:human· 2 Approach:machine learning (classical)· 2 Assay:protein sequence· 2 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Chen‐Hsiang SheniD· 2 shared Jing ZhouiD· 2 shared John R. MascolaiD· 2 shared Nicole A. Doria‐RoseiD· 2 shared Peter D. KwongiD· 2 shared Reda RawiiD· 2 shared Andrea R. ShiakolasiD· 1 shared Anthony P. WestiD· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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2 shared papersBioinformatics

Chen‐Hsiang ShenORCID

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Author profile →

3 papers

Recent·Most cited

mtx-COBRA: Subcellular localization prediction for bacterial proteins

Isha Arora, Arkadij Kummer, Hao Zhou, Mihaela G. Gadjeva, Eric J. Ma, Gwo‐Yu Chuang, Edison Ong

mtx-COBRA improves subcellular localization prediction for bacterial proteins, outperforming PSORTb in accuracy for proteins with unknown localization.

Computers in Biology and Medicine · Feb 10, 2024Peer-reviewedBioinformatics

Accurate Prediction of Antibody Resistance in Clinical HIV-1 Isolates

Reda Rawi, Raghvendra Mall, Chen‐Hsiang Shen, S. Katie Farney, Andrea R. Shiakolas, Jing Zhou, Halima Bensmail, Tae‐Wook Chun, Nicole A. Doria‐Rose, Rebecca M. Lynch, John R. Mascola, Peter D. Kwong, Gwo‐Yu Chuang

The paper develops machine learning classifiers to predict HIV-1 resistance to 33 neutralizing antibodies with 96% accuracy using clinical isolates.

Scientific Reports · Oct 11, 2019Peer-reviewedBioinformatics

Structural survey of HIV-1-neutralizing antibodies targeting Env trimer delineates epitope categories and suggests vaccine templates

Gwo‐Yu Chuang, Jing Zhou, Reda Rawi, Chen‐Hsiang Shen, Zizhang Sheng, Anthony P. West, Baoshan Zhang, Tongqing Zhou, Robert T. Bailer, Nicole A. Doria‐Rose, Mark K. Louder, Krisha McKee, John R. Mascola, Pamela J. Björkman, Lawrence S. Shapiro, Peter D. Kwong

The paper analyzes HIV-1 broadly neutralizing antibodies to classify epitopes and identify potential vaccine candidates based on structural and immunological features.

bioRxiv · May 2, 2018 · PreprintBioinformatics