Author

Tommy J Sroka

Saarland UniversityORCID 0000-0002-9016-5989Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Organism:Xenopus· 1

Frequent Co-Authors

David U. MickiD· 2 shared Avishek PrasaiiD· 1 shared Florian T. MerkleiD· 1 shared Jan N. HanseniD· 1 shared Josefine Hoeren· 1 shared Karina von der MalsburgiD· 1 shared Kerstin FeisteliD· 1 shared Lea K. SanwaldiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

David U. MickORCID

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2 papers

Recent·Most cited

Proximity proteomics of primary cilia in human hypothalamic neurons

Viviana Macarelli, Tommy J Sroka, Jan N. Hansen, Ulrika Axelsson, David U. Mick, Florian T. Merkle

The paper identifies ciliary proteins in human hypothalamic neurons and finds new therapeutic targets for obesity, including LPAR1, which mediates ciliary shortening.

bioRxiv · May 11, 2025 · PreprintCell Biology

iAPEX: Improved APEX-based proximity labeling for subcellular proteomics using an enzymatic reaction cascade

Tommy J Sroka, Lea K. Sanwald, Avishek Prasai, Josefine Hoeren, Karina von der Malsburg, Valerie Chaumet, Per Haberkant, Kerstin Feistel, David U. Mick

The paper introduces iAPEX, an improved APEX-based proximity labeling method for live-cell proteomics, and applies it to study primary cilia in Xenopus laevis, identifying new ciliary proteins and validating existing ones.

bioRxiv · Jan 10, 2025 · PreprintBiochemistry