Marie A. Floryan

A mechanically actuated lung microvascular model reveals that breathing-like deformation enhances tumor cell extravasation

IntravChip: a vascularized and perfused microfluidic model of the primary tumor microenvironment to collect intravasated tumor cells

The paper introduces IntravChip, a microfluidic platform to study tumor cell intravasation and collect intravasated cells, showing it can quantify intravasation rates and test anti-metastatic drugs.

Measuring Perfusion Pressure and Flow Resistance in a Microfluidic Device Using an External Optical System

This study develops an optical system to measure perfusion pressure and flow resistance in microfluidic devices without contacting the fluid, validating its accuracy against hydrostatic methods.

ETV2 mediated differentiation of human pluripotent stem cells results in functional endothelial cells for engineering advanced vascularized microphysiological models

This study generates functional endothelial cells from human iPSCs using ETV2 overexpression, enabling the creation of vascularized microphysiological models.

Remodeling of self-assembled microvascular networks under long term flow

This study shows that long-term flow can maintain and remodel microvascular networks in a microphysiological system for 51 days, reducing inflammation and enabling vascular remodeling.