Aayush Kant

This study develops a model linking nuclear hydration to chromatin phase organization and mechanics, showing how osmotic and mechanical cues influence chromatin structure through water content and histone dynamics.

This study shows that long-term flow can maintain and remodel microvascular networks in a microphysiological system for 51 days, reducing inflammation and enabling vascular remodeling.

This study combines theoretical modeling and high-resolution imaging to reveal how chromatin-lamina interactions and environmental cues influence LAD formation and thickness in hMSCs.

O-SNAP extracts and classifies chromatin features from SMLM data, detecting subtle changes in chromatin organization across biological transitions.