Author

Szymon J. Ciesielski

University of Wisconsin–MadisonORCID 0000-0002-9041-7162Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Bartłomiej TomiczekiD· 1 shared Brenda A. SchilkeiD· 1 shared Elizabeth Anne CraigiD· 1 shared Igor GrochowinaiD· 1 shared Jacek CzubiD· 1 shared Jarosław MarszałekiD· 1 shared Łukasz NierzwickiiD· 1 shared Marta A. UzarskaiD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Bartłomiej TomiczekORCID

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1 paper

Recent·Most cited

Two-step mechanism of J-domain action in driving Hsp70 function

Bartłomiej Tomiczek, Wojciech Delewski, Łukasz Nierzwicki, Milena Stolarska, Igor Grochowina, Brenda A. Schilke, Rafał Dutkiewicz, Marta A. Uzarska, Szymon J. Ciesielski, Jacek Czub, Elizabeth Anne Craig, Jarosław Marszałek

The paper investigates the two-step mechanism of J-domain action in Hsp70 function, revealing how JDPs perturb Hsp70's intramolecular network and enable ATP hydrolysis through conserved and variable residues.

PLoS Computational Biology · Jun 1, 2020Peer-reviewedMolecular Biology