Molecular BiologyeLifePeer-reviewed
Programmed genome editing of the omega-1 ribonuclease of the blood fluke, Schistosoma mansoni
Wannaporn Ittiprasert, Victoria H. Mann, Shannon E. Karinshak…·Paul J. Brindley
This paper demonstrates CRISPR/Cas9-based genome editing in Schistosoma mansoni, successfully mutating the omega-1 gene and reducing Th2 cytokine responses and granuloma formation.
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