BioinformaticsbioRxivPreprint
Ground Truth-Based Evaluation of False Discovery Rate and Statistical Power in DIA Proteomics
Jay M. Yarbro, Ya Huang, Vishwajeeth Pagala…·Zuo-Fei Yuan
This study evaluates false discovery rate and statistical power in DIA proteomics using technical replicates and spike-in experiments, revealing discrepancies between nominal and true FDR and showing power dependence on fold change and abundance.
DOI 10.64898/2026.05.29.728747