Author
University of JohannesburgORCID 0000-0002-9058-1675Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Kenneth Austin, Vincent A Obakachi, Florence Lisa Muzenda…·Graham Chakafana
The paper reports high-resolution structures of T. cruzi glycolytic enzymes and identifies potential inhibitors through structural analysis and virtual screening.
Lester Takunda Sigauke, Jonathan T. Bvunzawabaya, Gabrielle Lê-Bury…·Nyaradzo T. L. Chigorimbo‐Murefu
This study explores using USP18 inhibition to achieve anti-HIV activity through molecular simulations, free-energy profiling, and multi-cellular assays, showing reversible non-competitive inhibition and potential for antiviral strategies.
Godlo Sesethu, Maxam Nombalentle, Mthembu Yamnkela…·Xolani Henry Makhoba
This paper investigates the computational interaction between polyamines and heat shock proteins in Plasmodium falciparum to identify potential drug targets for malaria treatment.