Author

Godwin Akpeko Dziwornu

University of Cape TownORCID 0000-0003-1668-8818Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

David G. RusselliD· 1 shared David W. GludishiD· 1 shared Diogo Rodrigo Magalhães MoreiraiD· 1 shared Françoise Benoit‐VicaliD· 1 shared Gabrielle Lê-BuryiD· 1 shared Grace MugumbateiD· 1 shared Helenita Costa QuadrosiD· 1 shared Jeanne Manaranche· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

David G. RussellORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJun 23, 2024

Accessing anti-HIV activity through the attenuation of USP18 activity: novel insights from molecular dynamic simulations, free-energy profiling, and multi-cellular inhibition assays

Lester Takunda Sigauke, Jonathan T. Bvunzawabaya, Gabrielle Lê-Bury…·Nyaradzo T. L. Chigorimbo‐Murefu

This study explores using USP18 inhibition to achieve anti-HIV activity through molecular simulations, free-energy profiling, and multi-cellular assays, showing reversible non-competitive inhibition and potential for antiviral strategies.

DOI 10.1101/2024.06.23.600290

humanproteomics

𝕏 PostBluesky

MicrobiologyAntimicrobial Agents and ChemotherapyPeer-reviewedJun 20, 2024

Characterization of antimalarial activity of artemisinin-based hybrid drugs

Helenita Costa Quadros, Lars Herrmann, Jeanne Manaranche…·Diogo Rodrigo Magalhães Moreira

This study characterizes the antimalarial activity of two artemisinin-based hybrid drugs against drug-sensitive and resistant Plasmodium falciparum parasites, finding that slow peroxide bond homolysis correlates with increased efficacy against resistant strains.

5 citations

humanproteomics

𝕏 PostBluesky