Author

Gabrielle Lê-Bury

Cornell UniversityORCID 0000-0002-4650-5990Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 3 Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Assay:proteomics· 3 Research Focus:drug response / drug discovery· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

David G. RusselliD· 3 shared David W. GludishiD· 3 shared Audrey DumasiD· 2 shared Florence NiedergangiD· 2 shared Floriane HeritiD· 2 shared Henry Charles MwandumbaiD· 2 shared Saikat BoliariD· 2 shared Alexander V. PredeusiD· 1 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersImmunology

David G. RussellORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

ImmunologybioRxivPreprintSep 4, 2026

Screening of epigenetic modifiers identifies novel host-directed agents that suppress HIV-1 replication in primary human macrophages

Gabrielle Lê-Bury, Christine Mandalasi, Jordan M. Rhen…·David G. Russell

This study identifies novel compounds that inhibit HIV-1 replication in primary human macrophages by targeting epigenetic regulators.

DOI 10.64898/2026.09.01.748500

humanexperimental assay

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MicrobiologybioRxivPreprintMar 6, 2026

The lysosomal glutamine transporter SLC38A7/SNAT7 modulates SAMHD1 antiviral activity and promotes HIV-1 production in human macrophages

Floriane Herit, Gabrielle Lê-Bury, Quentin Provôt…·Florence Niedergang

DOI 10.64898/2026.03.06.709337

humanproteomics

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MicrobiologyRetrovirologyPeer-reviewedFeb 11, 2026

Versatile HIV Rev-dependent reporter cell system for stringent and sensitive quantification of viral reservoirs, neutralizing antibodies, and restriction factors

Mark Spear, Joseph Choi, Brian Hetrick…·David W. Gludish

DOI 10.1186/s12977-026-00675-8

humanexperimental assay

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MicrobiologybioRxivPreprintSep 29, 2025

The unique lipopolysaccharide composition of Salmonella Typhimurium ST313 dampens pyroptosis and inflammasome activation and suppresses host cell death

Gabrielle Lê-Bury, Chantal Deschamps, Floriane Herit…·Florence Niedergang

This study identifies that the unique lipopolysaccharide (LPS) of Salmonella Typhimurium ST313 reduces pyroptosis and inflammasome activation in human macrophages, contributing to its pathogenicity.

DOI 10.1101/2025.09.29.679141

humanproteomics

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ImmunologybioRxivPreprintJun 23, 2024

Accessing anti-HIV activity through the attenuation of USP18 activity: novel insights from molecular dynamic simulations, free-energy profiling, and multi-cellular inhibition assays

Lester Takunda Sigauke, Jonathan T. Bvunzawabaya, Gabrielle Lê-Bury…·Nyaradzo T. L. Chigorimbo‐Murefu

This study explores using USP18 inhibition to achieve anti-HIV activity through molecular simulations, free-energy profiling, and multi-cellular assays, showing reversible non-competitive inhibition and potential for antiviral strategies.

DOI 10.1101/2024.06.23.600290

humanproteomics

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