Cross-Frequency Coupling as a Neural Substrate for Prediction Error Evaluation: A Laminar Neural Mass Modeling Approach
Giulio Ruffini, Edmundo Lopez-Sola, Raul Palma, Roser Sanchez-Todo, Jakub Vohryzek, Francesca Castaldo, Karl John Friston
This paper proposes that cross-frequency coupling (CFC) mechanisms in a laminar neural mass model support prediction error evaluation in predictive coding, with implications for disorders like Alzheimer's disease and the effects of serotonergic psychedelics.
Neural Computation · Jul 27, 2026Peer-reviewedNeuroscience