Author

Sarah Gunasekera

Brown UniversityORCID 0009-0004-5000-8630Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:database / resource· 1 Organism:Drosophila· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alger M. FredericksiD· 1 shared Allison J. TaggartiD· 1 shared Anastasia WelchiD· 1 shared Chaorui DuaniD· 1 shared Chien‐Ling LiniD· 1 shared Cory BowersiD· 1 shared Daxing GaoiD· 1 shared Erica LarschaniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperMolecular Biology

Alger M. FredericksORCID

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2 papers

Recent·Most cited

Mapping genome-wide RNA-RNA and RNA-DNA interactions in nuclear hubs of male and female Drosophila cells

Sarah Gunasekera, Megan Carlson, Mukulika Ray, Erica Larschan

This study maps sex-specific RNA-RNA and RNA-DNA interactions in Drosophila cells using RD-SPRITE, revealing CLAMP's role in spliceosome targeting and RNA regulation.

bioRxiv · Aug 6, 2026 · PreprintGenomics

Elevated levels of intracellular RNA lariats suppress the antiviral response

Chaorui Duan, Luke Buerer, Cory Bowers, Allison J. Taggart, Mara H. O’Brien, Sarah Gunasekera, Chien‐Ling Lin, Jing Wang, Yi Zeng, Jonathan P. Staley, Alger M. Fredericks, Sean F. Monaghan, Anastasia Welch, Nathaniel E. Clark, Daxing Gao, , William Guy Fairbrother

The paper shows that accumulation of intracellular RNA lariats in DBR1-null cells reduces antiviral response by desensitizing dsRNA sensors.

The Journal of Experimental Medicine · Jan 15, 2026Peer-reviewedMolecular Biology