Claudia Avello Simões‐Pires

This paper describes a protocol for efficient CRISPR-mediated genomic editing in Epstein-Barr virus-transformed lymphoblastoid B cells using ssODN, achieving 20% successful editing and identifying structural mutations missed by targeted sequencing.

MAD-seq detects low-level mosaic chromosomal aneuploidy using a new sequencing assay and analysis method, revealing previously unrecognized aneuploidy in public datasets.

The paper describes two in vitro methods to measure HDAC6-Ub interaction independent of catalytic activity and suggests deacetylase domains modulate this interaction.

This study investigates how Toxoplasma gondii infection alters host transcriptional regulation by redistributing AP-1 transcription factor binding, leading to changes in chromatin accessibility and gene expression.