Author

Yamei Chen

Chinese Academy of Medical Sciences & Peking Union Medical CollegeORCID 0000-0002-9072-5157Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:whole-exome sequencing· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Alexandre ReubeniD· 1 shared Bonnie S. GlissoniD· 1 shared Carl Michael GayiD· 1 shared Carmen BehrensiD· 1 shared Chen Hsuan WuiD· 1 shared Chi-Wan B. Chow· 1 shared Chuanwang Miao· 1 shared Curtis E. GumbsiD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenomics

Alexandre ReubenORCID

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2 papers

Recent·Most cited

A body map of somatic mutagenesis in morphologically normal human tissues

Ruoyan Li, Lin Di, Jie Li, Wenyi Fan, Yachen Liu, Wenjia Guo, Weiling Liu, Lu Liu, Qiong Li, Liping Chen, Yamei Chen, Chuanwang Miao, Hongjin Liu, Yuqian Wang, Yuling Ma, , Chen Hsuan Wu

The paper maps somatic mutations and clonal expansions in normal human tissues across nine organs, revealing organ-specific patterns of mutation accumulation and clonal evolution.

Nature · Aug 25, 2021Peer-reviewedGenomics

Genomic and TCR Repertoire Intratumor Heterogeneity of Small-cell Lung Cancer and its Impact on Survival

Ming Chen, Runzhe Chen, Ying Jin, Jun Li, Jiexin Zhang, Junya Fujimoto, Won‐Chul Lee, Xin Yang Hu, Shawna Marie Hubert, Julie George, Xiao Hu, Yamei Chen, Carmen Behrens, Chi-Wan B. Chow, Hoa Hoang Ngoc Pham, , Jianjun J. Zhang

This study examines genomic and TCR repertoire heterogeneity in SCLC, finding that lower TCR heterogeneity and mutational burden correlate with better survival.

bioRxiv · Jun 30, 2020 · PreprintGenomics