Author

Chi-Wan B. Chow

The University of Texas MD Anderson Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 2 Genomics· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 4 Organism:human· 4 Approach:statistical model· 4 Assay:bulk RNA-seq· 2 Assay:whole-exome sequencing· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Carmen BehrensiD· 4 shared Ignacio Ivan WistubaiD· 4 shared Jianhua ZhangiD· 4 shared Jianjun J. ZhangiD· 4 shared John Victor HeymachiD· 4 shared Junya FujimotoiD· 4 shared P. Andrew FutrealiD· 4 shared Alexandre ReubeniD· 3 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersGenetic & Genomic Medicine

Carmen BehrensORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Immune evolution from preneoplasia to invasive lung adenocarcinomas and underlying molecular features

Hitoshi Dejima, Xin Yang Hu, Runzhe Chen, Jiexin Zhang, Junya Fujimoto, Edwin Roger Parra, Cara Haymaker, Shawna Marie Hubert, Dzifa Y. Duose, Luisa Maren Solis, Dan Su, Junya Fukuoka, Kazuhiro Tabata, Hoa Hoang Ngoc Pham, Nicholas McGranahan, , Jianjun J. Zhang

The paper investigates how anti-cancer immunity evolves from preneoplasia to invasive lung adenocarcinomas, identifying changes in immune response and molecular features that may facilitate immune evasion.

Nature Communications · May 11, 2021Peer-reviewedGenetic & Genomic Medicine

Evolution of DNA methylome from precancerous lesions to invasive lung adenocarcinomas

Xin Hu, Marcos R. Estecio, Runzhe Chen, Alexandre Reuben, Linghua Wang, Junya Fujimoto, Jian Carrot‐Zhang, Nicholas McGranahan, Lisha Ying, Junya Fukuoka, Chi-Wan B. Chow, Hoa Hoang Ngoc Pham, Myrna C.B. Godoy, Brett W. Carter, Carmen Behrens, , Jianjun J. Zhang

This study examines DNA methylation changes and intra-tumor heterogeneity in lung adenocarcinoma progression, finding increased methylation aberrations and immunosuppression in later-stage lesions.

Nature Communications · Jan 29, 2021Peer-reviewedGenetic & Genomic Medicine

The histologic phenotype of lung cancers may be driven by transcriptomic features rather than genomic characteristics

Ming Tang, Hussein A. Abbas, Marcelo Vailati Negrao, Maheshwari Ramineni, Xin Hu, Junya Fujimoto, A Reuben, Susan Varghese, Jianhua Zhang, Jun Li, Chi-Wan B. Chow, Xizeng Mao, Xingzhi Song, Won‐Chul Lee, Jia Wu, , Jianjun J. Zhang

This study shows that transcriptomic features, not genomic characteristics, drive the histologic phenotype of lung cancers.

bioRxiv · Jan 1, 2021 · PreprintGenomics

Genomic and TCR Repertoire Intratumor Heterogeneity of Small-cell Lung Cancer and its Impact on Survival

Ming Chen, Runzhe Chen, Ying Jin, Jun Li, Jiexin Zhang, Junya Fujimoto, Won‐Chul Lee, Xin Yang Hu, Shawna Marie Hubert, Julie George, Xiao Hu, Yamei Chen, Carmen Behrens, Chi-Wan B. Chow, Hoa Hoang Ngoc Pham, , Jianjun J. Zhang

This study examines genomic and TCR repertoire heterogeneity in SCLC, finding that lower TCR heterogeneity and mutational burden correlate with better survival.

bioRxiv · Jun 30, 2020 · PreprintGenomics