Author

Wenyi Fan

Chinese Academy of Medical Sciences & Peking Union Medical CollegeORCID 0000-0002-7875-7404Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Organism:mouse· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Jianbin WangiD· 2 shared Yanyi HuangiD· 2 shared Chen Hsuan WuiD· 1 shared Chenxi YuiD· 1 shared Chuanwang Miao· 1 shared Chunhong ZhengiD· 1 shared Deshu XuiD· 1 shared Dongfang LiuiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBioengineering

Jianbin WangORCID

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2 papers

Recent·Most cited

High-plex spatial RNA imaging in one round with conventional microscopes using color-intensity barcodes

Tianyi Chang, Shihui Zhao, Kunyue Deng, Zhizhao Liao, Mingchuan Tang, Yanxi Zhu, Wuji Han, Chenxi Yu, Wenyi Fan, Mengcheng Jiang, Guanbo Wang, Dongfang Liu, Jirun Peng, Yuhong Pang, Peng Fei, , Yanyi Huang

This paper introduces PRISM, a method for high-plex spatial RNA imaging using color intensity barcodes, validated across multiple tissues and showing the role of CAFs in tumor microenvironments.

Nature Biotechnology · Oct 30, 2025Peer-reviewedBioengineering

A body map of somatic mutagenesis in morphologically normal human tissues

Ruoyan Li, Lin Di, Jie Li, Wenyi Fan, Yachen Liu, Wenjia Guo, Weiling Liu, Lu Liu, Qiong Li, Liping Chen, Yamei Chen, Chuanwang Miao, Hongjin Liu, Yuqian Wang, Yuling Ma, , Chen Hsuan Wu

The paper maps somatic mutations and clonal expansions in normal human tissues across nine organs, revealing organ-specific patterns of mutation accumulation and clonal evolution.

Nature · Aug 25, 2021Peer-reviewedGenomics