Johannes Meiser

This study identifies mTORC2 as a convergent dependency in lung cancer that stabilizes HIF-1β to drive metabolic adaptation and tumor progression, revealing a therapeutic target in sphingolipid metabolism.

This study shows that the ketogenic diet reduces colorectal tumors in mice by altering the gut microbiome to increase stearic acid, which suppresses cancer cell growth and immune responses.

This study shows DJ-1 affects metabolism and immune response differently in Parkinson's disease and glioblastoma cells, with antioxidant treatment rescuing PD-related phenotypes.

This study shows insulin resistance in midbrain organoids reduces metabolic efficiency and neural activity, contributing to Parkinson's disease pathology.