Author

Marine Leclercq

University of LiègeORCID 0000-0002-3974-0060Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Pierre CloseiD· 2 shared Alex von KriegsheimiD· 1 shared Anaïs AstieriD· 1 shared Anisa AlijuiD· 1 shared Arnaud BlommeiD· 1 shared Carine FromentiD· 1 shared Célia Plisson‐ChastangiD· 1 shared Chinmayi PednekariD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Pierre CloseORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 3, 2026

mTORC2 stabilizes HIF-1β to coordinate metabolic adaptation in lung cancer

Morgane Paque, Ning An, Marine Leclercq…·Arnaud Blomme

This study identifies mTORC2 as a convergent dependency in lung cancer that stabilizes HIF-1β to drive metabolic adaptation and tumor progression, revealing a therapeutic target in sphingolipid metabolism.

DOI 10.64898/2026.09.02.748876

mouseexperimental assay

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Molecular BiologyHemaSpherePeer-reviewedJun 1, 2026

Translatome and translation dynamics analysis of a RiboCancer cell line panel reveals that leukemia-associated Rps15 mutations rewire translation through codon-specific tRNA accommodation defects.

Anaïs Astier, Marino Caruso, Stijn Vereecke…·Kim De Keersmaecker

The paper analyzes translatome and translation dynamics in RiboCancer cell lines to show that Rps15 mutations disrupt tRNA accommodation, affecting translation efficiency and transcriptional regulation in CLL.

2 citations

humanRibo-seq

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