Jeffrey C. Foster

This paper demonstrates a method to produce higher-molecular-weight nylons using chemically-synthesized diads and biosynthetic amide synthetases, expanding the range of usable precursors.

This study demonstrates that NIS synthetases can synthesize sequenced oligoamides from unprotected substrates, enabling the creation of novel sequence-defined polyamides with improved properties.

The paper identifies and characterizes diverse nylon hydrolases, showing that 40% of tested enzymes have significant activity, with some showing substrate selectivity for Nylon 6,6 over Nylon 6.