Author

Liangyu Qian

Oak Ridge National LaboratoryORCID 0009-0002-1202-9938Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Dana L. CarperiD· 2 shared Isaiah T. DishneriD· 2 shared Jeffrey C. FosteriD· 2 shared John F. CahilliD· 2 shared Joshua K. MicheneriD· 2 shared Nduka D. OgbonnaiD· 2 shared Vilmos KertésziD· 2 shared Jerry M. ParksiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

Dana L. CarperORCID

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2 papers

Recent·Most cited

Improved nylon polymerization using amide diads

Liangyu Qian, Isaiah T. Dishner, Dana L. Carper, Jerry M. Parks, Vilmos Kertész, Nicholas T Zolnierczuk, Nduka D. Ogbonna, Nikki A. Thiele, John F. Cahill, Jeffrey C. Foster, Joshua K. Michener

This paper demonstrates a method to produce higher-molecular-weight nylons using chemically-synthesized diads and biosynthetic amide synthetases, expanding the range of usable precursors.

Green Chemistry · Jan 1, 2026Peer-reviewedBiochemistry

Regioselective biosynthesis of oligoamides as precursors for sequence-controlled co-polyamides

Liangyu Qian, Isaiah T. Dishner, Nikolas Capra, Dana L. Carper, Nduka D. Ogbonna, Vilmos Kertész, John F. Cahill, Jeffrey C. Foster, Joshua K. Michener

This study demonstrates that NIS synthetases can synthesize sequenced oligoamides from unprotected substrates, enabling the creation of novel sequence-defined polyamides with improved properties.

bioRxiv · Nov 3, 2025 · PreprintBiochemistry