Author

Jenny C. Pessa

Åbo Akademi UniversityORCID 0000-0002-9113-6784Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Lea SistoneniD· 3 shared Alejandro J. Da SilvaiD· 2 shared Hendrik S. E. HästbackaiD· 2 shared Mikael Christer PuustineniD· 2 shared Adelina RabeniusiD· 1 shared Anniina VihervaaraiD· 1 shared Benjamin Thomas GoultiD· 1 shared Bina PrajapatiiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersCell Biology

Lea SistonenORCID

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3 papers

Recent·Most cited

Dynamic HSF2 regulation drives breast cancer progression by steering the balance between proliferation and invasion

Jenny C. Pessa, Oona Paavolainen, Mikael Christer Puustinen, Hendrik S. E. Hästbacka, Alejandro J. Da Silva, Sandra Pihlström, Silvia Gramolelli, Pia Boström, Pauliina Hartiala, Emilia Peuhu, Jenny Joutsen, Lea Sistonen

This study shows that dynamic regulation of HSF2 drives breast cancer progression by balancing proliferation and invasion through TGF-β signaling.

Science Advances · Sep 3, 2025Peer-reviewedCell Biology

A subpopulation of Talin 1 resides in the nucleus and regulates gene expression

Alejandro J. Da Silva, Hendrik S. E. Hästbacka, Mikael Christer Puustinen, Jenny C. Pessa, Jens C. Luoto, Erika Sundström, Benjamin Thomas Goult, Guillaume Jacquemet, Eva Henriksson, Lea Sistonen

This study identifies a nuclear subpopulation of Talin 1 that regulates gene expression in human breast epithelial cells.

iScience · Jan 5, 2025Peer-reviewedMolecular Biology

Waves of transcription drive erythroid differentiation and launch the NRF2-activated antioxidant program

Ingrid Karppi, Jenny C. Pessa, Adelina Rabenius, Samu V. Himanen, Bina Prajapati, Emilia Barkman Jonsson, Maria Kristina Vartiainen, Lea Sistonen, Anniina Vihervaara

The paper tracks transcription during erythroid differentiation and identifies NRF2's role in initiating an antioxidant program without oxidative stress.

bioRxiv · Jul 12, 2024 · PreprintGenomics