This study identifies the role of Hippo signaling in regulating cuticle pigmentation and dopamine metabolism in Drosophila through genetic and transcriptomic analyses.

PLoS Genetics · Aug 21, 2026Peer-reviewedGenetics

RNAi-based screen for pigmentation in Drosophila melanogaster reveals regulators of brain dopamine and sleep

Samantha L. Deal, Danqing Bei, Shelley Gibson, Harim Delgado-Seo, Yoko Fujita, Kyla Wilwayco, Elaine Seto, Amita Sehgal, Shinya Yamamoto

The paper identifies regulators of dopamine and sleep in Drosophila by screening genes affecting cuticle pigmentation, finding novel genes like mask that influence dopamine metabolism and behavior.

iScience · Dec 11, 2025Peer-reviewedNeuroscience

A Zika virus protein expression screen in Drosophila to investigate targeted host pathways during development

Nichole Link, J. Michael Harnish, Brooke Hull, Shelley Gibson, Miranda Dietze, Uchechukwu E. Mgbike, Silvia Medina-Balcazar, Priya S. Shah, Shinya Yamamoto

This study uses Drosophila to express Zika virus proteins and identifies phenotypes and host pathways disrupted by the virus during development.

Disease Models & Mechanisms · Jan 12, 2024Peer-reviewedDevelopmental Biology