Author

Christophe Varin

Université Libre de BruxellesORCID 0000-0002-9150-0654Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Assay:imaging· 1 Approach:statistical model· 1

Frequent Co-Authors

Alban de Kerchove d’ExaerdeiD· 3 shared Amandine CorniliD· 2 shared Bruno Giros AiD· 2 shared Patricia BonnavioniD· 2 shared Andrea ContiniiD· 1 shared Anna PetitboniD· 1 shared Asma OummadiiD· 1 shared Aurélie De Groote· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersNeuroscience

Alban de Kerchove d’ExaerdeORCID

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3 papers

Recent·Most cited

Unexpected contributions of striatal projection neurons coexpressing dopamine D1 and D2 receptors in balancing motor control

Patricia Bonnavion, Christophe Varin, Gohar Fakhfouri, Pilar Martinez Olondo, Aurélie De Groote, Amandine Cornil, Ramiro Lorenzo Lopez, Elisa Pozuelo Fernández, Elsa Isingrini, Quentin Rainer, Kathleen Xu, Eleni T. Tzavara, Érika Vigneault, Sylvie Dumas, Alban de Kerchove d’Exaerde, Bruno Giros A

The paper identifies D1/D2 coexpressing striatal projection neurons as critical for modulating motor function through interactions with D1- and D2-SPNs.

Nature Neuroscience · Jul 4, 2024Peer-reviewedNeuroscience

Nucleus accumbens D1- and D2-expressing neurons control the balance between feeding and activity-mediated energy expenditure

Roman Walle, Anna Petitbon, Giulia R. Fois, Christophe Varin, Enrica Montalban, Lola Hardt, Andrea Contini, María Florencia Angelo, Mylene Potier, Rodrigue Ortolé, Asma Oummadi, Véronique De Smedt, Roger A.H. Adan, Bruno Giros A, Francis Chaouloff, , Pierre Trifilieff

This study investigates the role of NAc D1 and D2 neurons in balancing feeding and exercise-mediated energy expenditure in mice, finding that manipulating these neurons affects energy balance and weight.

Nature Communications · Mar 21, 2024Peer-reviewedNeuroscience

Complementary coding of behaviors in striatal pathways supports a dual selection-suppression function

Christophe Varin, Amandine Cornil, Delphine Houtteman, Patricia Bonnavion, Alban de Kerchove d’Exaerde

The paper uses calcium imaging and supervised learning to show that direct and indirect striatal pathways encode behaviors through activation and silencing, respectively, supporting a dual selection-suppression function.

bioRxiv · Jun 20, 2022 · PreprintNeuroscience