Bruno Giros A

This study shows that chronic fluoxetine's antidepressant effects and neurogenesis require the dopamine D2 receptor, with implications for treatment response and drug interactions.

This study investigates sex-dependent cross-resilience to social defeat and learned helplessness stress models, revealing sex-specific molecular and behavioral patterns linked to BDNF-ERK signaling and norepinephrine.

This study links early-life stress outcomes to sex-dependent locus coeruleus-norepinephrine system activation in mice, revealing distinct behavioral and neurobiological patterns.

The paper investigates how childhood abuse affects the locus coeruleus-noradrenergic system in post-mortem brain samples, finding reduced neuron density and differential gene expression in resilient individuals.

The paper investigates how childhood abuse affects microglial markers and perineuronal nets in the ventromedial prefrontal cortex of individuals who died by suicide.

This study identifies proteomic changes in the human male olfactory bulb associated with depression, highlighting astrocytic dysfunction and species-specific differences in mouse models.

The paper identifies D1/D2 coexpressing striatal projection neurons as critical for modulating motor function through interactions with D1- and D2-SPNs.

This study examines CS disaccharide sulfation patterns in human and mouse brains, finding regional and species-specific differences and showing ELS does not affect PNN labeling patterns.

This study investigates the role of NAc D1 and D2 neurons in balancing feeding and exercise-mediated energy expenditure in mice, finding that manipulating these neurons affects energy balance and weight.

This study shows that methamphetamine exposure in mice induces infradian locomotor rhythms and mania-like behaviors, which depend on dopamine neurons projecting to the nucleus accumbens.

This study investigates the effects of brain-specific noradrenergic depletion on behavior and gene expression, finding anxiolytic effects and altered gene regulation in vulnerable brain regions.

This study shows that chronic dopamine transporter blockade in the mouse hippocampus causes learning and memory deficits, which are partially reversed by D2 receptor antagonists.

This study shows that reduced VMAT2 in astrocytes of the mouse medial prefrontal cortex leads to excessive grooming and anxiety-like behavior, with synaptic changes in the dorsal striatum.

This paper shows that d-amphetamine and methylphenidate increase GluA1 phosphorylation at Ser845 in mouse cerebellar Bergmann Glia Cells via norepinephrine signaling.