Romina Barría

Differential Assembly of Native ENaC Complexes Across Mouse Epithelial Tissues

This study uses a knock-in mouse model to analyze native ENaC complexes in different tissues, revealing tissue-specific differences in channel abundance and complex size.

Hypoxia-inducible factor 1 protects neurons from Sarm1-mediated neurodegeneration

The paper identifies HIF-1 as a regulator of Sarm1-mediated neurodegeneration, showing that stabilized HIF-1 prevents NAD+ loss and protects neurons.

An Ionic Sensor acts in Parallel to dSarm to Promote Neurodegeneration

The paper identifies dWnk as an ionic/osmotic sensor that promotes neurodegeneration alongside dSarm in Drosophila, converging on Axundead for axon death.

Glial TGFβ activity promotes axon survival in peripheral nerves

The paper identifies glial TGFβ signaling as essential for axon survival and shows its loss leads to age-dependent neurodegeneration.