Susanne Kleber

This paper introduces scReMeMber-Seq, a method to reconstruct single-cell trajectories by linking past and present transcriptomes using methylation-based memory recording.

The paper uses single-cell triple-omics to show DNA methylation patterns are key to stemness in adult brain cells, especially under ischemic conditions.

The paper introduces a GUI-based software for efficient Bayesian clustering of single-molecule localization microscopy data, improving speed and usability.

The paper identifies AAV variants that efficiently target adult neural stem cells in the subventricular zone, enabling genetic modification for potential regenerative therapies.

The paper shows that posttranscriptional regulation, specifically translational repression, controls the onset of differentiation in adult neural stem cells.

The paper shows that cell-cell contact influences tyrosine kinase activity, determining whether CD95 activation leads to apoptosis or proliferation in cancer cells.