Author

Lukas P. M. Kremer

German Cancer Research CenterORCID 0000-0003-3170-6295Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Ana Martín-VillalbaiD· 3 shared Santiago CerrizuelaiD· 3 shared Simon AndersiD· 3 shared Susanne KleberiD· 2 shared Alexander LaureiD· 1 shared Anna K. Marciniak-CzochraiD· 1 shared Aylin Korkmaz· 1 shared Dirk GrimmiD· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersNeuroscience

Ana Martín-VillalbaORCID

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3 papers

Recent·Most cited

NeuroscienceNaturePeer-reviewedSep 4, 2024

Single-cell triple-omics uncovers DNA methylation as key feature of stemness in the healthy and ischemic adult brain

Lukas P. M. Kremer, Santiago Cerrizuela, Hadil El‐Sammak…·Ana Martín-Villalba

The paper uses single-cell triple-omics to show DNA methylation patterns are key to stemness in adult brain cells, especially under ischemic conditions.

58 citationstop 1%

humanscRNA-seq

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BioinformaticsNature MethodsPeer-reviewedJul 31, 2024

Analyzing single-cell bisulfite sequencing data with MethSCAn

Lukas P. M. Kremer, Martina Maria Braun, Svetlana Ovchinnikova…·Simon Anders

The paper introduces MethSCAn, a tool for analyzing scBS data that improves methylation quantification and DMR detection, enhancing cell type discrimination with fewer cells.

30 citationstop 5%

DNA methylationstatistical model

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NeurosciencebioRxivPreprintMar 5, 2021

In vivo high-throughput screening of novel adeno-associated viral capsids targeting adult neural stem cells in the subventricular zone

Sascha Dehler, Lukas P. M. Kremer, Santiago Cerrizuela…·Ana Martín-Villalba

The paper identifies AAV variants that efficiently target adult neural stem cells in the subventricular zone, enabling genetic modification for potential regenerative therapies.

2 citations

mousebulk RNA-seq

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