Lisa Tietze

High-resolution mapping of Sigma Factor DNA Binding Sequences using Artificial Promoters, RNA Aptamers and Deep Sequencing

The paper maps sigma54 DNA binding sequences in Pseudomonas putida using a data-driven approach combining DNA libraries, RNA aptamers, and deep sequencing, revealing 64,966 distinct motifs.

Engineering Artificial 5' Regulatory Sequences for Thermostable Protein Expression in the Extremophile Thermus thermophilus

This study develops and validates artificial 5' regulatory sequences for enhancing thermostable protein expression in Thermus thermophilus.

mCherry contains a fluorescent protein isoform that interferes with its reporter function

The paper identifies a short fluorescent protein isoform in mCherry that causes background fluorescence and proposes a modified version to improve reporter function.

Hypothalamic glucocorticoid receptor in CRF neurons is essential for HPA axis habituation to repeated stressor

The paper shows that glucocorticoid receptors in CRF neurons are essential for HPA axis habituation to repeated stressors by modulating inhibitory tone and dampening activation.

The role of m6A-RNA methylation in stress response regulation

This paper investigates how m6A RNA methylation in the brain is regulated by stress and shows its role in fear memory, transcriptome response, and synaptic plasticity, with implications for stress-related disorders.