Daniel H. O’Connor

The paper introduces a high-density Neuropixels 2.0 Quad Base probe with 1536 channels, demonstrating its ability to capture brain-wide neural activity and reveal new insights into motor decision signals and functional subnetworks in mice.

This study investigates how stickiness information is encoded in whisker-surface interactions and neuronal responses in rodents.

This study investigates how mice adjust tongue movements based on somatosensory feedback, showing that orofacial cortical circuits dynamically update motor plans on a lick-by-lick timescale.

This paper introduces Opto-Myomatrix, a device for optogenetic muscle activation and EMG recording, achieving high optical output and low electrode impedance.

The paper shows that muscle spindle afferents encode complex jaw movements during a lick sequence task, with their coding changing across task phases.

This study shows that mice can adapt to altered somatotopic maps in the whisker somatosensory cortex, maintaining accurate sensorimotor representations despite abnormal bilateral whisker representations.

The paper shows how mice adjust motor execution sensitivity to external inputs based on sensorimotor context using optogenetic stimulation and neural activity analysis.

This study shows that Syngap1 in cortical neurons is essential for sensorimotor integration and perception by shaping neural dynamics and connectivity.

The paper examines sensory and motor signals in mouse somatosensory cortex during a whisker detection task, finding that choice-related activity varies by pathway and congruence.

This study investigates the neural basis of mechanosensation in the mouse tongue, identifying Piezo2+ trigeminal neurons and distinct mechanoreceptor types in lingual papillae.

This paper introduces an optogenetic method for perturbing muscles in transgenic mice, enabling simultaneous EMG recording and optical stimulation to study neuromuscular control.

The paper investigates how mice encode and use rule information in a sensory selection task, showing that preparatory activity in motor cortex reflects task rules and is necessary for rule-guided behavior.

The paper introduces Myomatrix arrays, a high-resolution electrode technology for recording muscle activity from motor units across species during natural behaviors.

The paper examines the temporal relationships between locus coeruleus spiking, somatosensory cortex activity, and pupil diameter in mice during a tactile detection task, finding that pupil diameter is not a reliable stationary index of LC activity.

The paper investigates tactile-auditory integration in mouse somatosensory cortices using two-photon imaging, finding robust inhibition in S2 and suggesting a local inhibitory circuit for spectral selection of inputs.

This study identifies a functional cortical network involved in controlling sensorimotor sequences in mice through a novel licking task and electrophysiological analysis.

The paper investigates how whisker motion is encoded by mechanoreceptors across different facial regions in mice, finding that whisker mechanoreceptors provide the best encoding, with additional contributions from other facial regions.