Author
Biomedical Primate Research CentreORCID 0000-0002-9198-8020Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Shusruto Rishik, Erik Nutma, Nicole Ludwig…·Andreas Keller
The paper identifies age-related miRNA deregulation patterns in aging rhesus macaques, highlighting tissue and sex-specific changes and cross-species conservation.
Giorgia Tosoni, Dilara Ayyildiz, Sarah Snoeck…·Evgenia Salta
The paper identifies unique transcriptional profiles of immature neurons in aged human hippocampus across healthy, Alzheimer's disease, and resilient conditions, linking them to homeostasis and cognitive resilience.
Ingrid H.C.H.M. Philippens, Kinga P. Böszörményi, Jacqueline A. M. Wubben…·Ernst J. Verschoor
This study shows SARS-CoV-2 infection in macaques leads to brain inflammation and Lewy body formation, suggesting potential long-term neurological effects.
Isadora C. Pereira Matias, Luan Pereira Diniz, Isabella Vivarini Damico…·Flávia Carvalho Alcântara Gomes
This study identifies loss of lamin-B1 and nuclear deformations as markers of astrocyte senescence in vitro and in aged human hippocampus.
Tamar Smit, Paul R. Ormel, Jacqueline A. Sluijs…·Vanessa Donega
This study examines the transcriptomic response of human monocyte-derived microglia-like cells to Aβ1-42 oligomers, finding increased metallothionein expression and no inflammatory or HAM/DAM profiles.
Astrid M. Alsema, Qiong Jiang, Laura Kracht…·Bart J. L. Eggen
The paper profiles microglia transcriptomes in AD donors and non-demented elderly using bulk and single-cell RNA sequencing, finding no significant differences in gene expression or subcluster composition.