Author

Astrid M. Alsema

University Medical Center GroningenORCID 0009-0001-2549-409XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Anneke MiedemaiD· 2 shared Bart J. L. EggeniD· 2 shared Emma GerritsiD· 2 shared Susanne M. KooistraiD· 2 shared Astrid WachteriD· 1 shared Elly M. HoliD· 1 shared Erik BoddekeiD· 1 shared Evelyn M. Wesseling· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersNeuroscience

Anneke MiedemaORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintMar 4, 2024

Identification of regional astrocyte heterogeneity associated with cuprizone-induced de- and remyelination using spatial transcriptomics

Anneke Miedema, Marion H. C. Wijering, Astrid M. Alsema…·Susanne M. Kooistra

This paper uses spatial transcriptomics to identify regional astrocyte heterogeneity in cuprizone-induced demyelination and remyelination, revealing differential gene expression patterns across brain regions.

1 citation

mousespatial transcriptomics

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NeuroscienceFrontiers in Molecular NeurosciencePeer-reviewedOct 28, 2020

Profiling microglia from AD donors and non-demented elderly in acute human post-mortem cortical tissue

Astrid M. Alsema, Qiong Jiang, Laura Kracht…·Bart J. L. Eggen

The paper profiles microglia transcriptomes in AD donors and non-demented elderly using bulk and single-cell RNA sequencing, finding no significant differences in gene expression or subcluster composition.

84 citationstop 4%

humanbulk RNA-seq

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