STING dampens the unfolded protein response to enable the presentation of self-antigens on MHC-I during inflammation.
Ahmed M. Fahmy, Ali Ahmadi, Joël Lanoix…·Michel Desjardins
The paper shows STING dampens the unfolded protein response to allow self-antigen presentation on MHC-I during inflammation, linking it to immune regulation in Parkinson's disease.