Author

Ahmed M. Fahmy

Aligning Science Across Parkinson'sORCID 0000-0003-0444-383XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:differential expression· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Michel DesjardinsiD· 3 shared Erwin SchurriD· 2 shared Heidi May McBrideiD· 2 shared Joël LanoixiD· 2 shared Pierre ThibaultiD· 2 shared Samantha GruenheidiD· 2 shared Yong Zhong XuiD· 2 shared Ajitha ThanabalasuriariD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersImmunology

Michel DesjardinsORCID

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3 papers

Recent·Most cited

ImmunologyCell ReportsPeer-reviewedJun 1, 2026

STING dampens the unfolded protein response to enable the presentation of self-antigens on MHC-I during inflammation.

Ahmed M. Fahmy, Ali Ahmadi, Joël Lanoix…·Michel Desjardins

The paper shows STING dampens the unfolded protein response to allow self-antigen presentation on MHC-I during inflammation, linking it to immune regulation in Parkinson's disease.

1 citation

mouseproteomics

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Cell BiologyJournal of Cell SciencePeer-reviewedMay 28, 2026

LRRK2 mutations block NCOA4 trafficking upon iron overload leading to ferroptotic death

Andrés Goldman, Mai Nguyen, Joël Lanoix…·Heidi May McBride

The paper shows LRRK2 mutations impair NCOA4 trafficking during iron overload, causing ferroptotic cell death in macrophages.

3 citationstop 1%

mouseproteomics

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Immunologynpj Parkinson s DiseasePeer-reviewedAug 29, 2025

LRRK2 G2019S mutation incites increased cell-intrinsic neutrophil effector functions and intestinal inflammation in a model of infectious colitis

Jessica Pei, Nathalia Luisa Oliveira, Sherilyn Junelle Recinto…·Samantha Gruenheid

This study shows that the LRRK2 G2019S mutation enhances neutrophil effector functions and drives intestinal inflammation in a mouse model of infectious colitis.

4 citations

mousescRNA-seq

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