Jan Schwenzfeier

Tensile Expansion Mass Spectrometry for single cell metabolomics imaging

Tensile stretching of live, unfixed OVCAR8 cells on a fibronectin-functionalized double-network hydrogel expands them about 1.7x linearly, enabling single-cell MALDI metabolite imaging on unmodified commercial instruments.

LipidQMap - An Open-Source Tool for Quantitative Mass Spectrometry Imaging of Lipids

LipidQMap is an open-source tool for processing quantitative mass spectrometry imaging lipidomics data, enabling accurate and reproducible spatial lipid quantification across MSI platforms.

Histology-Guided Single-Cell Mass Spectrometry Imaging using Integrated Bright-field and Fluorescence Microscopy

This paper integrates MALDI-MSI with bright-field and fluorescence microscopy to correlate lipid profiles with morphological and protein features at the single-cell level.

Single-cell mass spectrometry imaging combined with immunofluorescence reveals neutrophil heterogeneity in inflammation

The paper combines single-cell mass spectrometry imaging and immunofluorescence to identify pathogenic neutrophils in liver cirrhosis patients.