Author

Adrien Lupieri

Brigham and Women's HospitalORCID 0000-0002-9245-0169Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Aruna D. PradhaniD· 1 shared Elena Rabkin AikawaiD· 1 shared Katelyn A. PereziD· 1 shared Luisa WeißiD· 1 shared Mandy E TurneriD· 1 shared Mark C. BlaseriD· 1 shared Masanori AikawaiD· 1 shared Paul M. RidkeriD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

Aruna D. PradhanORCID

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1 paper

Recent·Most cited

Selective PPAR-α activation with pemafibrate attenuates macrophage-mediated progression of calcific aortic valve disease

Mandy E Turner, Yuto Nakamura, Takeshi Tanaka, Mark C. Blaser, Taku Kasai, Adrien Lupieri, Shinsuke Itoh, Rile Ge, Katelyn A. Perez, Rei Itagawa, Luisa Weiß, Takehito Okui, Yusuke Sasaki, Aruna D. Pradhan, Peter Libby, , Elena Rabkin Aikawa

This study shows pemafibrate reduces calcific aortic valve disease by modulating macrophage-VIC interactions, independent of lipid lowering.

bioRxiv · Dec 19, 2025 · PreprintPharmacology & Toxicology