Mark C. Blaser

This study shows pemafibrate reduces calcific aortic valve disease by modulating macrophage-VIC interactions, independent of lipid lowering.

This study identifies sex-specific proteomic differences in calcific aortic valve stenosis, revealing distinct molecular mechanisms in males and females.

The paper develops a cross-species proteomics pipeline to distinguish donor and host ECM proteins in explanted biomaterials, showing that single-species analysis leads to inaccurate quantification.

This study identifies EV-driven endothelial communication in human carotid atherosclerosis, showing increased angiogenic activity in symptomatic plaques.

The paper isolates and analyzes extracellular vesicles from atherosclerotic plaques and aortic valves, identifying shared and distinct molecular pathways involved in calcification.