Author

Jaesoo Jung

University of AlbertaORCID 0000-0002-9247-1066Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Edward N. SchmidtiD· 3 shared Matthew Scott MacauleyiD· 3 shared Ratmir DerdaiD· 2 shared A. Michael DowneyiD· 1 shared Ana GimenoiD· 1 shared Caishun LiiD· 1 shared Caleb Loo· 1 shared Chris D. St. LaurentiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersBiochemistry

Edward N. SchmidtORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BiochemistryJournal of the American Chemical SocietyPeer-reviewedSep 9, 2026

Non-Carbohydrate Inhibitors of Sialic Acid-binding Immunomodulatory-type Lectin-7 (Siglec-7) Discovered from Genetically Encoded Bicyclic Peptide Libraries

Danial Yazdan, A. Michael Downey, Ana Gimeno…·Ratmir Derda

This paper discovers non-carbohydrate inhibitors of Siglec-7:GD3 interactions using BiGEL libraries and validates their potency through SPR, ELISA, and NMR.

DOI 10.1021/jacs.6c14068

proteomicsdeep learning

Molecular BiologybioRxivPreprintJan 7, 2026

Siglec-7 and -15 recognize repeated clustered sulfo-sialo O-glycan motifs on select O-glycoproteins

Felix Goerdeler, Daniël L. A. H. Hornikx, Vera T.C. Valckx…·Yoshiki Narimatsu

This study identifies that Siglec-7 and -15 recognize repeated clustered sulfo-sialo O-glycan motifs on specific O-glycoproteins, enhancing selectivity through multivalent interactions.

5 citations

humanproteomics

BiochemistryScience AdvancesPeer-reviewedNov 12, 2025

An ultrasensitive and modular platform to detect Siglec ligands and control immune cell function

Zeinab Jame-Chenarboo, Edward N. Schmidt, Madeline C. Crichton…·Matthew Scott Macauley

The paper develops Siglec-liposomes to detect Siglec ligands and modulate immune cell function, showing they enhance T cell proliferation.

6 citations

humanexperimental assay