Yoshiki Narimatsu

This paper introduces a method to measure spontaneous curvature in cellular membranes using tether pulling and simulations, revealing baseline negative curvature and its modulation by treatments.

This study shows that agalactosylated IgG N-glycans in RA reduce neutrophilic inflammation by decreasing FcγR binding and downstream signaling, suggesting they may act as a compensatory anti-inflammatory mechanism.

This paper develops a chemical genetic strategy to manipulate proteoglycan glycan attachment sites in mammalian cells using modified xylosyltransferases.

This study identifies that Siglec-7 and -15 recognize repeated clustered sulfo-sialo O-glycan motifs on specific O-glycoproteins, enhancing selectivity through multivalent interactions.

This study identifies biantennary N-glycans as receptors for MARTX toxins in Vibrio vulnificus, showing their role in pathogenesis and broad cell targeting.

The paper identifies a specific O-glucose glycan extension on NOTCH1 EGF10 that impacts ligand binding and signaling, revealing new enzymatic pathways and structural features of Notch glycosylation.