Qing Deng

This study develops hPSC-derived FAP CAR neutrophils to target cardiac fibrosis, showing in vitro cytotoxicity and improved left ventricular ejection fraction in a mouse MI model.

scChat is a large language model co-pilot for scRNA-seq analysis that integrates contextual reasoning to improve hypothesis generation and experimental design.

CalciumInsights provides a user-friendly tool for analyzing calcium signals across multiple organisms and tissues without requiring programming expertise.

This study identifies RABEP1 as a key regulator of neutrophil migration by promoting endosomal recycling, Rac activation, and actin polymerization in zebrafish and human cells.

This study shows ROS inhibit myosin phosphorylation to counteract wound contraction, delay closure, and impair regrowth, while chronic ROS depletion alters tissue stiffness and impairs healing.

This study identifies Kir7.1's role in maintaining membrane potential and directional sensing during neutrophil chemotaxis, showing its necessity for polarized depolarization and chemotactic movement.

This paper develops a CRISPR/Cas9 system for neutrophil-specific gene disruption in zebrafish and demonstrates its utility in studying gene function.