Author

Chang Ding

Purdue University West LafayettePrimary ORCID profile (0000-0001-5550-4685 · 3 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Chang DingiD3 papers · Helmholtz Centre for Environmental Research

Biology Disciplines

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Cell Biology· 3 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:zebrafish· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 1 Assay:electrophysiology· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Qing DengiD· 4 shared Conwy Zheng· 2 shared Guangjun ZhangiD· 2 shared Ramizah SyahirahiD· 2 shared Yueyang WangiD· 2 shared Abby Pei Lemke· 1 shared Adrián Buganza TepoleiD· 1 shared Alan Y. Hsu· 1 shared

Activity by Year

2021-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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4 shared papersCell Biology

Qing DengORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

RABEP1 amplifies front signaling in neutrophil migration

Daniel H. Kim, Ramizah Syahirah, Conwy Zheng, Chang Ding, Alan Y. Hsu, Sheng Liu, Jun Wan, Qing Deng

This study identifies RABEP1 as a key regulator of neutrophil migration by promoting endosomal recycling, Rac activation, and actin polymerization in zebrafish and human cells.

bioRxiv · May 8, 2025 · PreprintCell Biology

Reactive Oxygen Species Counteract Wound Contraction and Promote Wound Healing

Chang Ding, Linlin Li, Yueyang Wang, Hong-Anh A. Nguyen, Deva D. Chan, David M. Umulis, Adrián Buganza Tepole, Qing Deng

This study shows ROS inhibit myosin phosphorylation to counteract wound contraction, delay closure, and impair regrowth, while chronic ROS depletion alters tissue stiffness and impairs healing.

bioRxiv · Mar 27, 2025 · PreprintCell Biology

Inwardly rectifying potassium channels regulate membrane potential polarization and direction sensing during neutrophil chemotaxis

Tianqi Wang, Daniel H Kim, Chang Ding, Dingxun Wang, Weiwei Zhang, Martin R. Silic, Xi Cheng, Kunming Shao, T. W. Ku, Conwy Zheng, Junkai Xie, Chongli Yuan, Alexander A. Chubykin, Christopher J. Staiger, Guangjun Zhang, Qing Deng

This study identifies Kir7.1's role in maintaining membrane potential and directional sensing during neutrophil chemotaxis, showing its necessity for polarized depolarization and chemotactic movement.

bioRxiv · Mar 6, 2025 · PreprintCell Biology

A CRISPR/Cas9 vector system for neutrophil-specific gene disruption in zebrafish

Yueyang Wang, Alan Yi-Hui Hsu, Eric M. Walton, Sung Jun Park, Ramizah Syahirah, Tianqi Wang, Wenqing Zhou, Chang Ding, Abby Pei Lemke, Guangjun Zhang, David M. Tobin, Qing Deng

This paper develops a CRISPR/Cas9 system for neutrophil-specific gene disruption in zebrafish and demonstrates its utility in studying gene function.

Journal of Cell Science · Mar 15, 2021Peer-reviewedGenetics