Ectopically expressed Airn lncRNA deposits Polycomb with a potency that rivals Xist
Jackson B. Trotman, Aki K. Braceros, Steve R. Bischoff, McKenzie M. Murvin, Samuel P. Boyson, Rachel E. Cherney, Quinn E. Eberhard, Elizabeth W. Abrash, Dale O. Cowley, J. Mauro Calabrese
The paper shows that Airn lncRNA can deposit Polycomb with potency comparable to Xist when expressed at similar levels, but Xist is more potent when promoter activation is equal.
bioRxiv · May 9, 2023 · PreprintMolecular Biology