Author
University of North Carolina at Chapel HillORCID 0000-0003-3133-2393Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Andrea Ascura, Stephen Clarke, Andrew F. Livingston…·Manuel Ascano
The paper identifies SPEN-driven m6A regulation as a key factor in henipavirus infection by analyzing host-virus RNA interactions using VIR-CLASP.
Jackson B. Trotman, Alessandro Porrello, Scott A. Schactler…·J. Mauro Calabrese
The paper identifies how Xist Repeat A recruits SPEN via SR proteins to induce gene silencing, revealing a role for splicing factors in this process.
Jackson B. Trotman, Aki K. Braceros, Steve R. Bischoff…·J. Mauro Calabrese
The paper shows that Airn lncRNA can deposit Polycomb with potency comparable to Xist when expressed at similar levels, but Xist is more potent when promoter activation is equal.
Aki K. Braceros, Megan D. Schertzer, Arina D. Omer…·J. Mauro Calabrese
The paper shows that the lncRNA Airn recruits Polycomb Repressive Complexes to silence genes during mouse embryogenesis through chromatin contacts and regulatory elements.
Jackson B. Trotman, David M. Lee, Rachel E. Cherney…·J. Mauro Calabrese
The paper identifies SPEN-independent transcriptional antiterminator activity in the 5' end of Xist that promotes full-length RNA production and resists silencing.